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Efficacy profile of the CYD-TDV dengue vaccine revealed by Bayesian survival analysis of individual-level phase III data

BACKGROUND: Sanofi-Pasteur’s CYD-TDV is the only licensed dengue vaccine. Two phase three trials showed higher efficacy in seropositive than seronegative recipients. Hospital follow-up revealed increased hospitalisation in 2–5- year-old vaccinees, where serostatus and age effects were unresolved. ME...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Laydon, Daniel J, Dorigatti, Ilaria, Hinsley, Wes R, Nedjati-Gilani, Gemma, Coudeville, Laurent, Ferguson, Neil M
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8321579/
https://ncbi.nlm.nih.gov/pubmed/34219653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.65131
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