Diverse Molecular Mechanisms Contribute to Differential Expression of Human Duplicated Genes

Emerging evidence links genes within human-specific segmental duplications (HSDs) to traits and diseases unique to our species. Strikingly, despite being nearly identical by sequence (>98.5%), paralogous HSD genes are differentially expressed across human cell and tissue types, though the underly...

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Detalhes bibliográficos
Publicado no:Mol Biol Evol
Main Authors: Shew, Colin J, Carmona-Mora, Paulina, Soto, Daniela C, Mastoras, Mira, Roberts, Elizabeth, Rosas, Joseph, Jagannathan, Dhriti, Kaya, Gulhan, O’Geen, Henriette, Dennis, Megan Y
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8321529/
https://ncbi.nlm.nih.gov/pubmed/34009325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msab131
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