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Short- and long-term effects on reproductive parameters of female Wistar rats after exposure to rosuvastatin starting in pre-puberty

Statins are a class of drugs that act lowering lipid levels by inhibiting cholesterol biosynthesis. Additionally, statins can act by “pleiotropic effects”, related to the inhibition of synthesis of the other mevalonate pathway products. Rosuvastatin is a third-generation statin and has shown better...

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Detalhes bibliográficos
Publicado no:Curr Res Toxicol
Main Authors: Barros, Jorge W.F., Tonon, Karolina S., Borges, Cibele S., Silva, Patrícia V., Lozano, Ana F.Q., Pacheco, Tainá L., Anselmo-Franci, Janete A., Kempinas, Wilma G.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8320644/
https://ncbi.nlm.nih.gov/pubmed/34345844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.crtox.2020.11.002
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