Dietary administration of β-ionone epoxide to Sprague-Dawley rats for 90 days

In a 90-day GLP-compliant study groups of Sprague-Dawley rats (10/sex/group) were fed diets containing β-ionone epoxide, a fragrance material and a flavoring substance, at dietary concentrations providing target intakes of 0, 20, 40 and 80 mg/kg bw/day. There were no deaths and no adverse changes in...

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Veröffentlicht in:Curr Res Toxicol
Hauptverfasser: Lu, Vivian, Bastaki, Maria, Api, Anne Marie, Aubanel, Michel, Bauter, Mark, Cachet, Thierry, Demyttenaere, Jan, Diop, Maodo Malick, Harman, Christie L., Hayashi, Shim-mo, Krammer, Gerhard, Mendes, Odete, Renskers, Kevin J., Schnabel, Jürgen, Taylor, Sean V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8320606/
https://ncbi.nlm.nih.gov/pubmed/34345860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.crtox.2021.05.001
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