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Antigen identification for HLA class I- and II-restricted T cell receptors using cytokine-capturing antigen-presenting cells

A major limitation to understanding the associations of human leukocyte antigen (HLA) and CD8(+) and CD4(+) T cell receptor (TCR) genes with disease pathophysiology is the technological barrier of identifying which HLA molecules, epitopes, and TCRs form functional complexes. Here we present a high-t...

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Detalhes bibliográficos
Publicado no:Sci Immunol
Main Authors: Lee, Mark N., Meyerson, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8320540/
https://ncbi.nlm.nih.gov/pubmed/33483338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.abf4001
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