Targeting Neoepitopes to Treat Solid Malignancies: Immunosurgery

Successful outcome of immune checkpoint blockade in patients with solid cancers is in part associated with a high tumor mutational burden (TMB) and the recognition of private neoantigens by T-cells. The quality and quantity of target recognition is determined by the repertoire of ‘neoepitope’-specif...

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Опубликовано в: :Front Immunol
Главные авторы: de Sousa, Eric, Lérias, Joana R., Beltran, Antonio, Paraschoudi, Georgia, Condeço, Carolina, Kamiki, Jéssica, António, Patrícia Alexandra, Figueiredo, Nuno, Carvalho, Carlos, Castillo-Martin, Mireia, Wang, Zhe, Ligeiro, Dário, Rao, Martin, Maeurer, Markus
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2021
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8320363/
https://ncbi.nlm.nih.gov/pubmed/34335558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.592031
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