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Sensitivity of cohesin–chromatin association to high-salt treatment corroborates non-topological mode of loop extrusion

Cohesin is a key organizer of chromatin folding in eukaryotic cells. The two main activities of this ring-shaped protein complex are the maintenance of sister chromatid cohesion and the establishment of long-range DNA–DNA interactions through the process of loop extrusion. Although the basic princip...

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Bibliografske podrobnosti
izdano v:Epigenetics Chromatin
Main Authors: Golov, Arkadiy K., Golova, Anastasia V., Gavrilov, Alexey A., Razin, Sergey V.
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8320178/
https://ncbi.nlm.nih.gov/pubmed/34321070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-021-00411-w
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