Human Norovirus NTPase Antagonizes Interferon-β Production by Interacting With IkB Kinase ε

Human norovirus (HuNoV) is the leading cause of epidemic acute gastroenteritis worldwide. Type I interferons (IFN)-α/β are highly potent cytokines that are initially identified for their essential roles in antiviral defense. It was reported that HuNoV infection did not induce IFN-β expression but wa...

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Bibliographic Details
Published in:Front Microbiol
Main Authors: Zheng, Zifeng, Li, Yuncheng, Zhang, Mudan, Liu, Yalan, Fu, Ming, Gong, Sitang, Hu, Qinxue
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8319745/
https://ncbi.nlm.nih.gov/pubmed/34335514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2021.687933
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