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Spectroscopic studies on photodegradation of atorvastatin calcium

In this work, the photodegradation process of atorvastatin calcium (ATC) is reported as depending on: (1) the presence and the absence of excipients in the solid state; (2) the chemical interaction of ATC with phosphate buffer (PB) having pH equal to 7 and 8; and (3) hydrolysis reaction of ATC in th...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Oprica, Madalina, Iota, Miruna, Daescu, Monica, Fejer, Szilard N., Negrila, Catalin, Baibarac, Mihaela
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8319406/
https://ncbi.nlm.nih.gov/pubmed/34321518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94693-5
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