An NK cell line (NK92-41BB) expressing high levels of granzyme is engineered to express the high affinity chimeric genes CD16/CAR

Natural killer (NK) cells are known to play a role in mediating innate immunity and have been implicated in mediating anti-tumor responses via antibody-dependent cell-mediated cytotoxicity (ADCC) based on the reactivity of CD16 with the Fc region of human IgG1 antibodies. The NK-92 cell line, devoid...

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Vydáno v:Cytotechnology
Hlavní autoři: Zhao, Hui, Zhou, Zhenlong, Li, Guangmeng, Liu, Gang, Lin, Shuyin, Chen, Wei, Xiong, Sheng
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2021
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8319282/
https://ncbi.nlm.nih.gov/pubmed/34349345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-021-00476-1
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