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Eco-friendly stability-indicating RP-HPTLC method for sildenafil analysis, characterization and biological evaluation of its oxidized stress degradation product

A feasible and cost effective reverse-phase high-performance thin layer chromatography (RP-HPTLC) based method was developed for the quantification of sildenafil (SLD) using eco-friendly EtOH:H(2)O (9.5:0.5 v/v) as mobile phase. SLD was subjected to stress conditions according to the International C...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Abdel-Kader, Maged S., Alam, Prawez, Soliman, Gamal A., Al-Shdefat, Ramadan, Afzal, Obaid
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8319155/
https://ncbi.nlm.nih.gov/pubmed/34321578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94854-6
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