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High-fat diet induces neuroinflammation and reduces the serotoninergic response to escitalopram in the hippocampus of obese rats

Clinical studies indicate that obese individuals have an increased risk of developing co-morbid depressive illness and that these patients have reduced responses to antidepressant therapy, including selective serotonin reuptake inhibitors (SSRIs). Obesity, a condition of chronic mild inflammation in...

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Detalhes bibliográficos
Publicado no:Brain Behav Immun
Main Authors: Hersey, Melinda, Woodruff, Jennifer L., Maxwell, Nicholas, Sadek, Alia T., Bykalo, Maria K., Bain, Ian, Grillo, Claudia A., Piroli, Gerardo G., Hashemi, Parastoo, Reagan, Lawrence P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8319113/
https://ncbi.nlm.nih.gov/pubmed/34010713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2021.05.010
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