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High-risk endometrial cancer proteomic profiling reveals that FBXW7 mutation alters L1CAM and TGM2 protein levels

BACKGROUND. FBXW7 is frequently somatically mutated in grade 3 endometrioid endometrial cancers (G3EECs) and serous ECs (SECs), which are high-risk cancers associated with poor outcomes and in need of novel treatment options. We aimed to determine the proteomic effects of three FBXW7 mutations in hi...

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Detalhes bibliográficos
Publicado no:Cancer
Main Authors: Urick, Mary Ellen, Yu, Eun-Jeong, Bell, Daphne W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8319067/
https://ncbi.nlm.nih.gov/pubmed/33872388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.33567
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