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High-risk endometrial cancer proteomic profiling reveals that FBXW7 mutation alters L1CAM and TGM2 protein levels
BACKGROUND. FBXW7 is frequently somatically mutated in grade 3 endometrioid endometrial cancers (G3EECs) and serous ECs (SECs), which are high-risk cancers associated with poor outcomes and in need of novel treatment options. We aimed to determine the proteomic effects of three FBXW7 mutations in hi...
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| Published in: | Cancer |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2021
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8319067/ https://ncbi.nlm.nih.gov/pubmed/33872388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.33567 |
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