Structural basis of early translocation events on the ribosome

Peptide-chain elongation during protein synthesis entails sequential aminoacyl-tRNA selection and translocation reactions that proceed rapidly (2–20 per second) and with a low error rate (around 10(−3) to 10(−5) at each step) over thousands of cycles(1). The cadence and fidelity of ribosome transit...

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Pubblicato in:Nature
Autori principali: Rundlet, Emily J., Holm, Mikael, Schacherl, Magdalena, Natchiar, S. Kundhavai, Altman, Roger B., Spahn, Christian M. T., Myasnikov, Alexander G., Blanchard, Scott C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8318882/
https://ncbi.nlm.nih.gov/pubmed/34234344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-021-03713-x
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