Effects of general versus subarachnoid anaesthesia on circadian melatonin rhythm and postoperative delirium in elderly patients undergoing hip fracture surgery: A prospective cohort clinical trial

BACKGROUND: Circadian rhythm disturbance is common postoperatively in older patients with hip fractures, which may contribute to the development of postoperative delirium (POD). As a reliable biomarker of endogenous circadian rhythms, melatonin regulates the sleep-wake cycle and environmental adapta...

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Bibliographische Detailangaben
Veröffentlicht in:EBioMedicine
Hauptverfasser: Song, Yanan, Liu, Yajie, Yuan, Yi, Jia, Xixi, Zhang, Wenchao, Wang, Geng, Jia, Yunyang, Wang, Xiaoxiao, Liu, Lei, Li, Weitian, Li, Xinping, Cai, Nan, Liu, Chang, Li, Yue, Han, Yongzheng, Zhou, Yang, Mi, Xinning, Shi, Chengmei, Wang, John Q., Vuylsteke, Alain, Guo, Xiangyang, Li, Zhengqian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2021
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8318871/
https://ncbi.nlm.nih.gov/pubmed/34280784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2021.103490
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