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The blood flow-klf6a-tagln2 axis drives vessel pruning in zebrafish by regulating endothelial cell rearrangement and actin cytoskeleton dynamics

Recent studies have focused on capillary pruning in various organs and species. However, the way in which large-diameter vessels are pruned remains unclear. Here we show that pruning of the zebrafish caudal vein (CV) from ventral capillaries of the CV plexus in different transgenic embryos is driven...

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Publicado en:PLoS Genet
Autores principales: Wen, Lin, Zhang, Tao, Wang, Jinxuan, Jin, Xuepu, Rouf, Muhammad Abdul, Luo, Desha, Zhu, Yuan, Lei, Daoxi, Gregersen, Hans, Wang, Yeqi, Wang, Guixue
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8318303/
https://ncbi.nlm.nih.gov/pubmed/34319989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009690
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