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Genotypes and phenotypes of G6PD deficiency among Indonesian females across diagnostic thresholds of G6PD activity guiding safe primaquine therapy of latent malaria

BACKGROUND: Plasmodium vivax occurs as a latent infection of liver and a patent infection of red blood cells. Radical cure requires both blood schizontocidal and hypnozoitocidal chemotherapies. The hypnozoitocidal therapies available are primaquine and tafenoquine, 8-aminoquinoline drugs that can pr...

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Détails bibliographiques
Publié dans:PLoS Negl Trop Dis
Auteurs principaux: Satyagraha, Ari Winasti, Sadhewa, Arkasha, Panggalo, Lydia Visita, Subekti, Decy, Elyazar, Iqbal, Soebianto, Saraswati, Mahpud, Nunung, Harahap, Alida Rosita, Baird, J. Kevin
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8318249/
https://ncbi.nlm.nih.gov/pubmed/34270547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0009610
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