The Basic Research of the Combinatorial Therapy of ABT-199 and Homoharringtonine on Acute Myeloid Leukemia

BACKGROUND: Existing research shows that ABT-199, as a first-line drug, have been widely used in hematological malignancies, especially in leukemia, but the clinical efficacy of single drug therapy was limited part of the reason was that BCL-2 inhibitors failure to target other anti-apoptotic BCL-2...

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Vydáno v:Front Oncol
Hlavní autoři: Shi, Yuanfei, Ye, Jing, Yang, Ying, Zhao, Yanchun, Shen, Huafei, Ye, Xiujin, Xie, Wanzhuo
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8317985/
https://ncbi.nlm.nih.gov/pubmed/34336680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.692497
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