Synthesis and biological evaluations of oleanolic acid indole derivatives as hyaluronidase inhibitors with enhanced skin permeability

Oleanolic acid (OA) is a natural cosmeceutical compound with various skin beneficial activities including inhibitory effect on hyaluronidase but the anti-hyaluronidase activity and mechanisms of action of its synthetic analogues remain unclear. Herein, a series of OA derivatives were synthesised and...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: He, Hao, Li, Huifang, Akanji, Toyosi, Niu, Shengli, Luo, Zhujun, Li, Dongli, Seeram, Navindra P., Wu, Panpan, Ma, Hang
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8317927/
https://ncbi.nlm.nih.gov/pubmed/34309457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2021.1956487
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