High Serine-arginine Protein Kinase 1 Expression with PTEN Loss Defines Aggressive Phenotype of Prostate Cancer Associated with Lethal Outcome and Decreased Overall Survival

BACKGROUND: Serine-arginine protein kinase 1 (SRPK1) has been implicated in prostate cancer (PCa) progression. However, its prognostic value and association with ERG and PTEN expression, two of the most common genetic alterations, have not been explored fully. OBJECTIVE: We assessed the prognostic v...

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Bibliografiske detaljer
Udgivet i:Eur Urol Open Sci
Main Authors: Abou-Ouf, Hatem, Assem, Hisham, Ghosh, Sunita, Karnes, R. Jeffrey, Stoletov, Konstantin, Palanisamy, Nallasivam, Lewis, John D., Bismar, Tarek A.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Prostate Cancer
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8317848/
https://ncbi.nlm.nih.gov/pubmed/34337483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.euros.2020.11.005
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