Distinct signatures of codon and codon pair usage in 32 primary tumor types in the novel database CancerCoCoPUTs for cancer-specific codon usage

BACKGROUND: Gene expression is highly variable across tissues of multi-cellular organisms, influencing the codon usage of the tissue-specific transcriptome. Cancer disrupts the gene expression pattern of healthy tissue resulting in altered codon usage preferences. The topic of codon usage changes as...

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Vydáno v:Genome Med
Hlavní autoři: Meyer, Douglas, Kames, Jacob, Bar, Haim, Komar, Anton A., Alexaki, Aikaterini, Ibla, Juan, Hunt, Ryan C., Santana-Quintero, Luis V., Golikov, Anton, DiCuccio, Michael, Kimchi-Sarfaty, Chava
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8317675/
https://ncbi.nlm.nih.gov/pubmed/34321100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-021-00935-6
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