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Catalytic asymmetric synthesis of spirocyclobutyl oxindoles and beyond via [2+2] cycloaddition and sequential transformations

Efficient asymmetric synthesis of a collection of small molecules with structural diversity is highly important to drug discovery. Herein, three distinct types of chiral cyclic compounds were accessible by enantioselective catalysis and sequential transformations. Highly regio- and enantioselective...

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Publicado en:Chem Sci
Autores principales: Zhong, Xia, Tan, Jiuqi, Qiao, Jianglin, Zhou, Yuqiao, Lv, Cidan, Su, Zhishan, Dong, Shunxi, Feng, Xiaoming
Formato: Artigo
Lenguaje:Inglês
Publicado: The Royal Society of Chemistry 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8317662/
https://ncbi.nlm.nih.gov/pubmed/34377393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1sc02681j
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