Učitavanje...

Mechanisms of acquired resistance of BRCA1/2-driven tumors to platinum compounds and PARP inhibitors

Molecular pathogenesis of tumors arising in BRCA1/2 germ-line mutation carriers usually includes somatic inactivation of the remaining allele of the involved gene. Consequently, BRCA1/2-driven cancers are sensitive to platinum-based therapy and poly (ADP-ribose) polymerase inhibitors (PARPi). Long-t...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:World J Clin Oncol
Glavni autori: Imyanitov, Evgeny, Sokolenko, Anna
Format: Artigo
Jezik:Inglês
Izdano: Baishideng Publishing Group Inc 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8317650/
https://ncbi.nlm.nih.gov/pubmed/34367927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5306/wjco.v12.i7.544
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!