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Heterologous Expression and Auto-Activation of Human Pro-Inflammatory Caspase-1 in Saccharomyces cerevisiae and Comparison to Caspase-8

Caspases are a family of cysteine proteases that play an essential role in inflammation, apoptosis, cell death, and development. Here we delve into the effects caused by heterologous expression of human caspase-1 in the yeast Saccharomyces cerevisiae and compare them to those of caspase-8. Overexpre...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Valenti, Marta, Molina, María, Cid, Víctor J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8317575/
https://ncbi.nlm.nih.gov/pubmed/34335569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.668602
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