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Identification of Hub Genes and Small Molecule Drugs Associated with Acquired Resistance to Gefitinib in Non-Small Cell Lung Cancer

Targeting EGFR, epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs), brings lights to the treatment of non-small cell lung cancer (NSCLC). Although T790M mutation responded as one of the main reasons of acquired resistance, still 15% of the resistance patients can't be expla...

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Bibliografske podrobnosti
izdano v:J Cancer
Main Authors: Li, Guangda, Ma, Yunfei, Yu, Mingwei, Li, Xiaoxiao, Chen, Xinjie, Gao, Yu, Cheng, Peiyu, Zhang, Ganlin, Wang, Xiaomin
Format: Artigo
Jezik:Inglês
Izdano: Ivyspring International Publisher 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8317531/
https://ncbi.nlm.nih.gov/pubmed/34335945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.56506
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