Spatial epi-proteomics enabled by histone post-translational modification analysis from low-abundance clinical samples

BACKGROUND: Increasing evidence linking epigenetic mechanisms and different diseases, including cancer, has prompted in the last 15 years the investigation of histone post-translational modifications (PTMs) in clinical samples. Methods allowing the isolation of histones from patient samples followed...

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Publicat a:Clin Epigenetics
Autors principals: Noberini, Roberta, Savoia, Evelyn Oliva, Brandini, Stefania, Greco, Francesco, Marra, Francesca, Bertalot, Giovanni, Pruneri, Giancarlo, McDonnell, Liam A., Bonaldi, Tiziana
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Methodology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8317427/
https://ncbi.nlm.nih.gov/pubmed/34315505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-021-01120-7
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