Fine-tuning the expression of pathway gene in yeast using a regulatory library formed by fusing a synthetic minimal promoter with different Kozak variants

BACKGROUND: Tailoring gene expression to balance metabolic fluxes is critical for the overproduction of metabolites in yeast hosts, and its implementation requires coordinated regulation at both transcriptional and translational levels. Although synthetic minimal yeast promoters have shown many adva...

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Udgivet i:Microb Cell Fact
Main Authors: Xu, Liping, Liu, Pingping, Dai, Zhubo, Fan, Feiyu, Zhang, Xueli
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8317321/
https://ncbi.nlm.nih.gov/pubmed/34320991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-021-01641-z
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