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Prediction Model for Cereblon Expression in Bone Marrow Plasma Cells Based on Blood Markers in Multiple Myeloma Patients

BACKGROUND: Cereblon (CRBN) is a direct target of immunomodulatory drugs (IMiDs) and is known to be sensitive and responsive to IMiD therapy. We evaluated CRBN expression in bone marrow plasma cells and analyzed whether CRBN expression was associated with multiple myeloma prognosis. Lastly, we devel...

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Publicado en:Front Oncol
Autores principales: Lee, Byung-Hyun, Kang, Ka-Won, Jeon, Min Ji, Yu, Eun Sang, Kim, Dae Sik, Lee, Se Ryeon, Sung, Hwa Jung, Park, Yong, Choi, Chul Won, Kim, Byung Soo
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316857/
https://ncbi.nlm.nih.gov/pubmed/34336672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.687361
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