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Knockdown screening of chromatin binding and regulatory proteins in zebrafish identified Suz12b as a regulator of tfpia and an antithrombotic drug target

Tissue factor pathway inhibitor (TFPI) is an anticoagulant protein that inhibits factor VIIa and Xa in the coagulation cascade. It has been shown that forkhead box P3 protein is a TFPI transcriptional repressor. However, there are no studies on chromatin remodeling that control TFPI expression. We h...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Raman, Revathi, Fallatah, Weam, Al Qaryoute, Ayah, Dhinoja, Sanchi, Jagadeeswaran, Pudur
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316476/
https://ncbi.nlm.nih.gov/pubmed/34315984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94715-2
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