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Knockdown screening of chromatin binding and regulatory proteins in zebrafish identified Suz12b as a regulator of tfpia and an antithrombotic drug target

Tissue factor pathway inhibitor (TFPI) is an anticoagulant protein that inhibits factor VIIa and Xa in the coagulation cascade. It has been shown that forkhead box P3 protein is a TFPI transcriptional repressor. However, there are no studies on chromatin remodeling that control TFPI expression. We h...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Raman, Revathi, Fallatah, Weam, Al Qaryoute, Ayah, Dhinoja, Sanchi, Jagadeeswaran, Pudur
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316476/
https://ncbi.nlm.nih.gov/pubmed/34315984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94715-2
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