Shotgun lipidomics of liver and brain tissue of Alzheimer’s disease model mice treated with acitretin

Alzheimer’s disease (AD) is a very frequent neurodegenerative disorder characterized by an accumulation of amyloid-β (Aβ). Acitretin, a retinoid-derivative and approved treatment for Psoriasis vulgaris, increases non-amyloidogenic Amyloid-Precursor-Protein-(APP)-processing, prevents Aβ-production an...

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Vydáno v:Sci Rep
Hlavní autoři: Lauer, Anna A., Janitschke, Daniel, dos Santos Guilherme, Malena, Nguyen, Vu Thu Thuy, Bachmann, Cornel M., Qiao, Sen, Schrul, Bianca, Boehm, Ulrich, Grimm, Heike S., Hartmann, Tobias, Endres, Kristina, Grimm, Marcus O. W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316403/
https://ncbi.nlm.nih.gov/pubmed/34315969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94706-3
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