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The Impact of Durvalumab on Local Regional Control in Stage III Non-Small Cell Lung Cancers Treated with Chemoradiation and on KEAP1/NFE2L2 Mutant Tumors

INTRODUCTION: KEAP1/NFE2L2 mutant NSCLCs are chemoradiation-resistant and at high-risk for local-regional failure (LRF) after concurrent chemoradiation (cCRT). To elucidate the impact of durvalumab on local-regional control, we assessed LRF in NSCLC patients treated with cCRT with and without durval...

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Publicado en:J Thorac Oncol
Autores principales: Shaverdian, Narek, Offin, Michael, Shepherd, Annemarie F., Simone, Charles B., Gelblum, Daphna Y., Wu, Abraham J., Hellmann, Matthew D., Rimner, Andreas, Paik, Paul K., Chaft, Jamie E., Gomez, Daniel R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316395/
https://ncbi.nlm.nih.gov/pubmed/33992811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtho.2021.04.019
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