The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology

Relapsing fever (RF), caused by spirochetes of the genus Borrelia, is a globally distributed, vector-borne disease with high prevalence in developing countries. To date, signaling pathways required for infection and virulence of RF Borrelia spirochetes are unknown. Cyclic di-AMP (c-di-AMP), synthesi...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Jackson-Litteken, Clay D., Ratliff, C. Tyler, Kneubehl, Alexander R., Siletti, Cheta, Pack, Lindsay, Lan, Renny, Huynh, TuAnh N., Lopez, Job E., Blevins, Jon S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316131/
https://ncbi.nlm.nih.gov/pubmed/33846120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00787-20
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