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Two Functionally Redundant FK506-Binding Proteins Regulate Multidrug Resistance Gene Expression and Govern Azole Antifungal Resistance

Increasing resistance to antifungal therapy is an impediment to the effective treatment of fungal infections. Candida glabrata is an opportunistic human fungal pathogen that is inherently less susceptible to cost-effective azole antifungals. Gain-of-function mutations in the Zn-finger pleiotropic dr...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Moirangthem, Romila, Kumar, Kundan, Kaur, Rupinder
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316114/
https://ncbi.nlm.nih.gov/pubmed/33722894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02415-20
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