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Two Functionally Redundant FK506-Binding Proteins Regulate Multidrug Resistance Gene Expression and Govern Azole Antifungal Resistance

Increasing resistance to antifungal therapy is an impediment to the effective treatment of fungal infections. Candida glabrata is an opportunistic human fungal pathogen that is inherently less susceptible to cost-effective azole antifungals. Gain-of-function mutations in the Zn-finger pleiotropic dr...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Moirangthem, Romila, Kumar, Kundan, Kaur, Rupinder
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316114/
https://ncbi.nlm.nih.gov/pubmed/33722894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02415-20
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