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In Vivo Generation of BK and JC Polyomavirus Defective Viral Genomes in Human Urine Samples Associated with Higher Viral Loads

Defective viral genomes (DVGs) are parasitic viral sequences containing point mutations, deletions, or duplications that might interfere with replication. DVGs are often associated with viral passage at high multiplicities of infection in culture systems but have been increasingly reported in clinic...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Addetia, Amin, Phung, Quynh, Bradley, Benjamin T., Lin, Michelle J., Zhu, Haiying, Xie, Hong, Huang, Meei-Li, Greninger, Alexander L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316075/
https://ncbi.nlm.nih.gov/pubmed/33827948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00250-21
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