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In Vitro and In Vivo Antifungal Activity of AmBisome Compared to Conventional Amphotericin B and Fluconazole against Candida auris

Antifungal activity of AmBisome against Candida auris was determined in vitro and in vivo. AmBisome showed MIC(50) and MIC(90) values of 1 and 2 μg/ml, respectively. Unlike conventional amphotericin B, significant in vivo efficacy was observed in the AmBisome 7.5 mg/kg treatment group in survival an...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Herrada, Janet, Gamal, Ahmed, Long, Lisa, Sanchez, Sonia P., McCormick, Thomas S., Ghannoum, Mahmoud A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316017/
https://ncbi.nlm.nih.gov/pubmed/33846131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00306-21
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