Manogepix, the Active Moiety of the Investigational Agent Fosmanogepix, Demonstrates In Vitro Activity against Members of the Fusarium oxysporum and Fusarium solani Species Complexes

We evaluated the in vitro activity of manogepix against Fusarium oxysporum and Fusarium solani species complex (FOSC and FSSC, respectively) isolates per CLSI document M38 broth microdilution methods. Manogepix demonstrated activity against both FOSC (MEC [minimum effective concentration] range, ≤0....

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Publicat a:Antimicrob Agents Chemother
Autors principals: Badali, Hamid, Patterson, Hoja P., Sanders, Carmita J., Mermella, Barbara, Gibas, Connie F. C., Ibrahim, Ashraf S., Shaw, Karen J., Wiederhold, Nathan P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2021
Matèries:
Susceptibility
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8315997/
https://ncbi.nlm.nih.gov/pubmed/33722886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02343-20
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