In Vitro and In Vivo Activities, Absorption, Tissue Distribution, and Excretion of OBP-4, a Potential Anti-Clostridioides difficile Agent

Clostridioides difficile infection (CDI) is considered a major concern of the health care system globally, with an increasing need for alternative therapies. OBP-4, a new oxazolidinone-fluoroquinolone hybrid with excellent in vitro activities and good safety, shows promising features as an antibacte...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Liu, Lili, Zhou, Xuzheng, Li, Bing, Cheng, Fusheng, Cui, Haifeng, Li, Jing, Zhang, Jiyu
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2021
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8315982/
https://ncbi.nlm.nih.gov/pubmed/33820771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00581-21
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