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Nucleolin Promotes IRES-Driven Translation of Foot-and-Mouth Disease Virus by Supporting the Assembly of Translation Initiation Complexes

Nucleolin (NCL), a stress-responsive RNA-binding protein, has been implicated in the translation of internal ribosome entry site (IRES)-containing mRNAs, which encode proteins involved in cell proliferation, carcinogenesis, and viral infection (type I IRESs). However, the details of the mechanisms b...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Han, Shichong, Wang, Xiaojia, Guan, Junyong, Wu, Jinen, Zhang, Yun, Li, Pinghua, Liu, Zaixin, Abdullah, Sahibzada Waheed, Zhang, Zhihui, Jin, Ye, Sun, Shiqi, Guo, Huichen
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8315980/
https://ncbi.nlm.nih.gov/pubmed/33853964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00238-21
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