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Ibrexafungerp Demonstrates In Vitro Activity against Fluconazole-Resistant Candida auris and In Vivo Efficacy with Delayed Initiation of Therapy in an Experimental Model of Invasive Candidiasis

Candida auris is an emerging pathogen that has rapidly spread to many countries on multiple continents. Invasive infections caused by this species are associated with significant mortality, and treatment options are limited due to antifungal resistance. Ibrexafungerp is the first-in-class member of...

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Библиографические подробности
Опубликовано в: :Antimicrob Agents Chemother
Главные авторы: Wiederhold, Nathan P., Najvar, Laura K., Olivo, Marcos, Morris, Kelsey N., Patterson, Hoja P., Catano, Gabriel, Patterson, Thomas F.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8315906/
https://ncbi.nlm.nih.gov/pubmed/33753333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02694-20
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