Chromatin Looping Links Target Genes with Genetic Risk Loci for Dermatological Traits

Chromatin looping between regulatory elements and gene promoters presents a potential mechanism whereby disease risk variants affect their target genes. In this study, we use H3K27ac HiChIP, a method for assaying the active chromatin interactome in two cell lines: keratinocytes and skin lymphoma–der...

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Vydáno v:J Invest Dermatol
Hlavní autoři: Shi, Chenfu, Ray-Jones, Helen, Ding, James, Duffus, Kate, Fu, Yao, Gaddi, Vasanthi Priyadarshini, Gough, Oliver, Hankinson, Jenny, Martin, Paul, McGovern, Amanda, Yarwood, Annie, Gaffney, Patrick, Eyre, Steve, Rattray, Magnus, Warren, Richard B., Orozco, Gisela
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2021
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8315765/
https://ncbi.nlm.nih.gov/pubmed/33607115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2021.01.015
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