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Nuclear Factor Erythroid 2-Related Factor 2-Histone Deacetylase 2 Pathway in the Pathogenesis of Refractory Sudden Sensorineural Hearing Loss and Glucocorticoid Resistance

INTRODUCTION: A significant number of sensorineural hearing loss (SSNHL) patients had no noticeable hearing improvement after glucocorticoid (GC) treatment. In the present study, we examined expression of the nuclear factor erythroid 2-related factor 2 (NRF2) and histone deacetylase 2 (HDAC2) in per...

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Detalhes bibliográficos
Publicado no:ORL J Otorhinolaryngol Relat Spec
Main Authors: Qi, Hui, Gao, Zi-Wen, Hou, Jie, Zhou, Qiongqiong, Ma, Wei, Dai, Yan-Hong, She, Wan-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8315675/
https://ncbi.nlm.nih.gov/pubmed/34091451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000515205
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