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Cancer stem cells, epithelial-mesenchymal transition, ATP and their roles in drug resistance in cancer

The cancer stem cell (CSC) state and epithelial-mesenchymal transition (EMT) activation are tightly interconnected. Cancer cells that acquire the EMT/CSC phenotype are equipped with adaptive metabolic changes to maintain low reactive oxygen species levels and stemness, enhanced drug transporters, an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Drug Resist
Hauptverfasser: Zhang, Haiyun, Steed, Alexander, Co, Milo, Chen, Xiaozhuo
Format: Artigo
Sprache:Inglês
Veröffentlicht: OAE Publishing Inc. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8315560/
https://ncbi.nlm.nih.gov/pubmed/34322664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20517/cdr.2021.32
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