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SpikChIP: a novel computational methodology to compare multiple ChIP-seq using spike-in chromatin

In order to evaluate cell- and disease-specific changes in the interacting strength of chromatin targets, ChIP-seq signal across multiple conditions must undergo robust normalization. However, this is not possible using the standard ChIP-seq scheme, which lacks a reference for the control of biologi...

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Bibliografiske detaljer
Udgivet i:NAR Genom Bioinform
Main Authors: Blanco, Enrique, Di Croce, Luciano, Aranda, Sergi
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8315120/
https://ncbi.nlm.nih.gov/pubmed/34327329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nargab/lqab064
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