Celastrol ameliorates vascular neointimal hyperplasia through Wnt5a-involved autophagy

Neointimal hyperplasia caused by the excessive proliferation of vascular smooth muscle cells (VSMCs) is the pathological basis of restenosis. However, there are few effective strategies to prevent restenosis. Celastrol, a pentacyclic triterpene, has been recently documented to be beneficial to certa...

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Dettagli Bibliografici
Pubblicato in:Int J Biol Sci
Autori principali: Shi, Ya-Ning, Liu, Le-Ping, Deng, Chang-Feng, Zhao, Tan-Jun, Shi, Zhe, Yan, Jian-Ye, Gong, Yong-Zhen, Liao, Duan-Fang, Qin, Li
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2021
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8315023/
https://ncbi.nlm.nih.gov/pubmed/34326694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.58715
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