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N6-methyladenosine methyltransferases: functions, regulation, and clinical potential

N6-methyladenosine (m6A) has emerged as an abundant modification throughout the transcriptome with widespread functions in protein-coding and noncoding RNAs. It affects the fates of modified RNAs, including their stability, splicing, and/or translation, and thus plays important roles in posttranscri...

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Bibliographische Detailangaben
Veröffentlicht in:J Hematol Oncol
Hauptverfasser: Huang, Wei, Chen, Tian-Qi, Fang, Ke, Zeng, Zhan-Cheng, Ye, Hua, Chen, Yue-Qin
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8313886/
https://ncbi.nlm.nih.gov/pubmed/34315512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-021-01129-8
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