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Deletion of TRPV3 and Ca(V)3.2 T-type channels in mice undermines fertility and Ca(2+) homeostasis in oocytes and eggs

Ca(2+) influx during oocyte maturation and after sperm entry is necessary to fill the internal Ca(2+) stores and for complete egg activation. We knocked out the transient receptor potential vanilloid member 3 (TRPV3) and the T-type channel, Ca(V)3.2, to determine their necessity for maintaining thes...

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Podrobná bibliografie
Vydáno v:J Cell Sci
Hlavní autoři: Mehregan, Aujan, Ardestani, Goli, Akizawa, Hiroki, Carvacho, Ingrid, Fissore, Rafael
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8313860/
https://ncbi.nlm.nih.gov/pubmed/34313315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.257956
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