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Negative Feedback Role of Astrocytes in Shaping Excitation in Brain Cell Co-cultures

Glial cells play an important role in maintaining neuronal homeostasis and may thus influence excitability in epileptogenesis. These cells in the brain have glutamate (Glu) transporters, which remove this neurotransmitter from the extracellular space. Lack of negative (−) feedback makes local neuron...

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Pubblicato in:Front Cell Neurosci
Autori principali: Khezerlou, Elnaz, Prajapati, Neela, DeCoster, Mark A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8313828/
https://ncbi.nlm.nih.gov/pubmed/34326721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2021.651509
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