Leukocytes with chromosome Y loss have reduced abundance of the cell surface immunoprotein CD99

Mosaic loss of chromosome Y (LOY) in immune cells is a male-specific mutation associated with increased risk for morbidity and mortality. The CD99 gene, positioned in the pseudoautosomal regions of chromosomes X and Y, encodes a cell surface protein essential for several key properties of leukocytes...

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Publicado no:Sci Rep
Main Authors: Mattisson, Jonas, Danielsson, Marcus, Hammond, Maria, Davies, Hanna, Gallant, Caroline J., Nordlund, Jessica, Raine, Amanda, Edén, Malin, Kilander, Lena, Ingelsson, Martin, Dumanski, Jan P., Halvardson, Jonatan, Forsberg, Lars A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8313698/
https://ncbi.nlm.nih.gov/pubmed/34312421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94588-5
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