Butyrophilin-like 2 regulates site-specific adaptations of intestinal γδ intraepithelial lymphocytes

Tissue-resident γδ intraepithelial lymphocytes (IELs) orchestrate innate and adaptive immune responses to maintain intestinal epithelial barrier integrity. Epithelia-specific butyrophilin-like (Btnl) molecules induce perinatal development of distinct Vγ TCR(+) IELs, however, the mechanisms that cont...

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Udgivet i:Commun Biol
Main Authors: Panea, Casandra, Zhang, Ruoyu, VanValkenburgh, Jeffrey, Ni, Min, Adler, Christina, Wei, Yi, Ochoa, Francisca, Schmahl, Jennifer, Tang, Yajun, Siao, Chia-Jen, Poueymirou, William, Espert, Jennifer, Lim, Wei Keat, Atwal, Gurinder S., Murphy, Andrew J., Sleeman, Matthew A., Hovhannisyan, Zaruhi, Haxhinasto, Sokol
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8313535/
https://ncbi.nlm.nih.gov/pubmed/34312491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02438-x
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