Linear Energy Transfer Incorporated Spot-Scanning Proton Arc Therapy Optimization: A Feasibility Study

PURPOSE: To integrate dose-averaged linear energy transfer (LET(d)) into spot-scanning proton arc therapy (SPArc) optimization and to explore its feasibility and potential clinical benefits. METHODS: An open-source proton planning platform (OpenREGGUI) has been modified to incorporate LET(d) into op...

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Vydáno v:Front Oncol
Hlavní autoři: Li, Xiaoqiang, Ding, Xuanfeng, Zheng, Weili, Liu, Gang, Janssens, Guillaume, Souris, Kevin, Barragán-Montero, Ana M., Yan, Di, Stevens, Craig, Kabolizadeh, Peyman
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8313436/
https://ncbi.nlm.nih.gov/pubmed/34327139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.698537
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